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Dieting / Supplement Discussion You eat like a pig. You'll never be a champion if you stuff yourself with that slop. Get in here.

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Old 12-11-2008, 04:28 AM   #1 (permalink)

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Icon4 The All-Encompassing Vitamin D Thread

Got this tid bit from Garrett at the Performance Menu.

Epidemic Influenza And Vitamin D



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Epidemiology and Infection, known as The Journal of Hygiene in Hope-Simpson's day, recently published our paper. The editor, Professor Norman Noah, knew Dr. Hope-Simpson and helped tremendously with the paper. In the paper, we detailed our theory that vitamin D is Hope-Simpson's long forgotten "seasonal stimulus." We proposed that annual fluctuations in vitamin D levels explain the seasonality of influenza. The periodic seasonal fluctuations in 25-hydroxy-vitamin D levels, which cause recurrent and predictable wintertime vitamin D deficiency, predispose human populations to influenza epidemics. We raised the possibility that influenza is a symptom of vitamin D deficiency in the same way that an unusual form of pneumonia (pneumocystis carinii) is a symptom of AIDS. That is, we theorized that George Bernard Shaw was right when he said, "the characteristic microbe of a disease might be a symptom instead of a cause."

In the paper, we propose that vitamin D explains the following 14 observations:

1. Why the flu predictably occurs in the months following the winter solstice, when vitamin D levels are at their lowest,

2. Why it disappears in the months following the summer solstice,

3. Why influenza is more common in the tropics during the rainy season,

4. Why the cold and rainy weather associated with El Nino Southern Oscillation (ENSO), which drives people indoors and lowers vitamin D blood levels, is associated with influenza,

5. Why the incidence of influenza is inversely correlated with outdoor temperatures,

6. Why children exposed to sunlight are less likely to get colds,

7. Why cod liver oil (which contains vitamin D) reduces the incidence of viral respiratory infections,

8. Why Russian scientists found that vitamin D-producing UVB lamps reduced colds and flu in schoolchildren and factory workers,

9. Why Russian scientists found that volunteers, deliberately infected with a weakened flu virus - first in the summer and then again in the winter - show significantly different clinical courses in the different seasons,

10. Why the elderly who live in countries with high vitamin D consumption, like Norway, are less likely to die in the winter,

11. Why children with vitamin D deficiency and rickets suffer from frequent respiratory infections,

12. Why an observant physician (Rehman), who gave high doses of vitamin D to children who were constantly sick from colds and the flu, found the treated children were suddenly free from infection,

13. Why the elderly are so much more likely to die from heart attacks in the winter rather than in the summer,

14. Why African Americans, with their low vitamin D blood levels, are more likely to die from influenza and pneumonia than Whites are.

Although our paper discusses the possibility that physiological doses of vitamin D (5,000 units a day) may prevent colds and the flu, and that physicians might find pharmacological doses of vitamin D (2,000 units per kilogram of body weight per day for three days) useful in treating some of the one million people who die in the world every year from influenza, we remind readers that it is only a theory. Like all theories, our theory must withstand attempts to be disproved with dispassionately conducted and well-controlled scientific experiments.








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Last edited by MikeMartial; 03-10-2009 at 11:27 AM.
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Old 12-11-2008, 04:40 AM   #2 (permalink)
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How different is supplemental VitD from the one you get from sun?
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Old 12-11-2008, 05:18 AM   #3 (permalink)

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Quote:
Originally Posted by stylesbjj View Post
How different is supplemental VitD from the one you get from sun?
I was wondering this this also. Does anyone know the answer?.

The article Vedic posted makes for some compelling arguments.
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Old 12-11-2008, 05:27 AM   #4 (permalink)

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Interesting stuff. Do the examples cited do a good job of taking account of other possible explanations? Just off the top of my head I can think of a couple alternative explanations for most of them. Depending upon the methodology of the studies it could go either way in my mind.
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Old 12-11-2008, 07:46 AM   #5 (permalink)
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Some interesting correlations, sure.

Vit D has been getting a LOT of good press lately, from everyone from Poliquin to those stupid morning news "health experts."
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Old 12-11-2008, 08:45 AM   #6 (permalink)
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Up into the wee hours posting about vitamin D, eh Vedic? When I get off shift and get home, I'll be able to add to this.

I agree, Xtrainer---Vitamin D seems like a daily topic. Based on what I've been reading and considering my northern climate, I've upped my intake to 3000IU a day. I even had my physician agree to do a 25(OH)D on me, but I'll have to wait 6 months for it.
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Old 12-11-2008, 08:52 AM   #7 (permalink)
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Quote:
Originally Posted by stylesbjj View Post
How different is supplemental VitD from the one you get from sun?
UV rays are converted to D3; supplements are usually D3, but I've seen D2 out there, also.
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Old 12-11-2008, 09:44 AM   #8 (permalink)

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Now you tell me.

I've been off all week purging from both ends with the stomach flu...

Good times.
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Old 12-11-2008, 10:00 AM   #9 (permalink)
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I'm wondering about overdose, actually I was curious about that before this article. At work we routinely fill prescriptions for 50,000 units of vitamin d, which is 50-80 times that of most over-the-counter D3 supplements.

I was under the impression that because vitamin d is fat soluble it is easier to overdose on. I've wanted to go on a 5,000+ unit regime for quite a while but was slightly concerned about that. Maybe it is a good question for a pharmacist, but in all likely-hood vedic would have a better answer.
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Old 12-11-2008, 10:52 AM   #10 (permalink)
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Quote:
Originally Posted by joshetc View Post
I'm wondering about overdose, actually I was curious about that before this article. At work we routinely fill prescriptions for 50,000 units of vitamin d, which is 50-80 times that of most over-the-counter D3 supplements.

I was under the impression that because vitamin d is fat soluble it is easier to overdose on. I've wanted to go on a 5,000+ unit regime for quite a while but was slightly concerned about that. Maybe it is a good question for a pharmacist, but in all likely-hood vedic would have a better answer.
From the Merck Manual:

"Because synthesis of 1,25(OH)<sub>2</sub>D (the most active ****bolite of vitamin D) is tightly regulated, vitamin D toxicity usually occurs only if excessive doses (prescription or megavitamin) are taken. Vitamin D 1000 μg (40,000 IU)/day produces toxicity within 1 to 4 mo in infants. In adults, taking 1250 μg (50,000 IU)/day for several months can produce toxicity. "
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