Football tackle...change levels and go for single/double leg takedown, drive them into the ground once you have a grip, and then shoot for side control in the transition.
I've done this easily to stronger and bigger people. Josh Barnett had a spot in The Human Weapon and he was teaching Jason Chambers and Bill Duff how to do it.
YouTube - Human Weapon MMA - Double Leg Takedown
I think pros like GSP or Hughes would stuff me or Sprawl in a cage, but it works on everyday people at the gym.
One of my coaches actually tries for wrist control and to wrap that arm across the neck. Once in side control, he's got you one handed and then rains elbows or punches to the face. Almost all of one of my high school buddies' fights ended up like this and he'd jack that other guy while on the ground with wrist control (he didn't train).