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I don't think it has "run it's course". Even though there are fighters who's general mentality is "Hey! I'll get one fight in the Octagon on tv and be satisfied". They'll usually be weeded out and the fighters who are legit will make it into the UFC.
People will tune in regardless who's fighting which makes the show a success. So unless people stop tuning in there's no reason to bring the show to an end.
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